Chemical and Biomolecular Sciences encompasses the study of analysing, transforming and manipulating substances and the molecular interpretation of the world around us. The Chemical and Biomolecular Sciences major is based on understanding molecules and how they are formed and interact and how molecules influence the structure and function of biological systems. The major emphasises chemistry at the interface of biology, enabling students to gain theoretical knowledge and practical experience in a range of subject areas, including: analytical chemistry physical chemistry organic chemistry biochemistry microbiology molecular biology genomics

For students from overseas, Macquarie uses an international selection rank to determine the minimum eligibility requirement for each undergraduate course. This rank has been converted into equivalent scores for various recognised international high school qualifications and university entrance examinations, including global qualifications like the International Baccalaureate (IB) and GCE A-Levels. All applicants for undergraduate coursework studies at Macquarie University are required to provide evidence of proficiency in English.